Somatic mutation detection using various targeted detection assays in paired samples of circulating tumor DNA, primary tumor and metastases from patients undergoing resection of colorectal liver metastases

Assessing circulating tumor DNA (ctDNA) is a promising method to evaluate somatic mutations from solid tumors in a minimally‐invasive way. In a group of twelve metastatic colorectal cancer (mCRC) patients undergoing liver metastasectomy, from each patient DNA from cell‐free DNA (cfDNA), the primary...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Beije, Nick, Helmijr, Jean C., Weerts, Marjolein J.A., Beaufort, Corine M., Wiggin, Matthew, Marziali, Andre, Verhoef, Cornelis, Sleijfer, Stefan, Jansen, Maurice P.H.M., Martens, John W.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423131/
https://ncbi.nlm.nih.gov/pubmed/28949453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.10.001
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