Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2

Hepatocellular carcinoma (HCC) is the most common type of liver cancer in humans. The focal adhesion tyrosine kinase (FAK) is often over-expressed in human HCC and FAK inhibition may reduce HCC cell invasiveness. However, the anti-oncogenic effect of FAK knockdown in HCC cells remains to be clarifie...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Gnani, Daniela, Romito, Ilaria, Artuso, Simona, Chierici, Marco, De Stefanis, Cristiano, Panera, Nadia, Crudele, Annalisa, Ceccarelli, Sara, Carcarino, Elena, D'Oria, Valentina, Porru, Manuela, Giorda, Ezio, Ferrari, Karin, Miele, Luca, Villa, Erica, Balsano, Clara, Pasini, Diego, Furlanello, Cesare, Locatelli, Franco, Nobili, Valerio, Rota, Rossella, Leonetti, Carlo, Alisi, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423113/
https://ncbi.nlm.nih.gov/pubmed/28338656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.34
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