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T-cells contribute to hypertension but not to renal injury in mice with subtotal nephrectomy

BACKGROUND: The pathological condition of chronic kidney disease may not be adequately recapitulated in immunocompromised mice due to the lack of T-cells, which are important for the development of hypertension and renal injury. We studied the role of the immune system in relation to salt-sensitive...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Oosterhuis, Nynke R., Papazova, Diana A., Gremmels, Hendrik, Joles, Jaap A., Verhaar, Marianne C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422945/
https://ncbi.nlm.nih.gov/pubmed/28482823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0555-0
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