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Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal

BACKGROUND AND PURPOSE: Whether NO, carbon monoxide (CO) and hydrogen sulfide (H(2)S) compensate for each other when one or more is depleted is unclear. Inhibiting NOS causes hypertension and kidney injury. Both global depletion of H(2)S by cystathionine γ-lyase (CSE) gene deletion and low levels of...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Wesseling, Sebastiaan, Fledderus, Joost O, Verhaar, Marianne C, Joles, Jaap A
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369267/
https://ncbi.nlm.nih.gov/pubmed/24597655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12674
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