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Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal

BACKGROUND AND PURPOSE: Whether NO, carbon monoxide (CO) and hydrogen sulfide (H(2)S) compensate for each other when one or more is depleted is unclear. Inhibiting NOS causes hypertension and kidney injury. Both global depletion of H(2)S by cystathionine γ-lyase (CSE) gene deletion and low levels of...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Wesseling, Sebastiaan, Fledderus, Joost O, Verhaar, Marianne C, Joles, Jaap A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369267/
https://ncbi.nlm.nih.gov/pubmed/24597655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12674
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