Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase

Estrogen and progesterone coupled with locally produced signaling molecules are essential for embryo implantation. However, the hierarchical landscape of the molecular pathways that governs this process remains largely unexplored. Here we show that the protein tyrosine phosphatase Shp2, a positive t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ran, Hao, Kong, Shuangbo, Zhang, Shuang, Cheng, Jianghong, Zhou, Chan, He, Bo, Xin, Qiliang, Lydon, John P., DeMayo, Francesco J., Feng, Gen-Sheng, Xia, Guoliang, Lu, Zhongxian, Wang, Chao, Wang, Haibin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422785/
https://ncbi.nlm.nih.gov/pubmed/28424251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700978114
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