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Using microsecond single-molecule FRET to determine the assembly pathways of T4 ssDNA binding protein onto model DNA replication forks

DNA replication is a core biological process that occurs in prokaryotic cells at high speeds (∼1 nucleotide residue added per millisecond) and with high fidelity (fewer than one misincorporation event per 10(7) nucleotide additions). The ssDNA binding protein [gene product 32 (gp32)] of the T4 bacte...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Phelps, Carey, Israels, Brett, Jose, Davis, Marsh, Morgan C., von Hippel, Peter H., Marcus, Andrew H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422767/
https://ncbi.nlm.nih.gov/pubmed/28416680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619819114
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