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Autoantibodies to box A of high mobility group box 1 in systemic lupus erythematosus

Autoantibodies to nuclear structures are a hallmark of systemic lupus erythematosus (SLE), including autoantibodies to nuclear protein high mobility group box 1 (HMGB1). HMGB1 consists of three separate domains: box A, box B and an acidic tail. Recombinant box A acts as a competitive antagonist for...

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Bibliografske podrobnosti
izdano v:Clin Exp Immunol
Main Authors: Schaper, F., de Leeuw, K., Horst, G., Maas, F., Bootsma, H., Heeringa, P., Limburg, P. C., Westra, J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422715/
https://ncbi.nlm.nih.gov/pubmed/28245520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12951
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