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Thyroid Hormone Induces PGC-1α during Dendritic Outgrowth in Mouse Cerebellar Purkinje Cells

Thyroid hormone 3,3′,5-Triiodo-L-thyronine (T3) is essential for proper brain development. Perinatal loss of T3 causes severe growth defects in neurons and glia, including strong inhibition of dendrite formation in Purkinje cells in the cerebellar cortex. Here we show that T3 promotes dendritic outg...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Hatsukano, Tetsu, Kurisu, Junko, Fukumitsu, Kansai, Fujishima, Kazuto, Kengaku, Mineko
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422430/
https://ncbi.nlm.nih.gov/pubmed/28536504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00133
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