Thyroid Hormone Induces PGC-1α during Dendritic Outgrowth in Mouse Cerebellar Purkinje Cells

Thyroid hormone 3,3′,5-Triiodo-L-thyronine (T3) is essential for proper brain development. Perinatal loss of T3 causes severe growth defects in neurons and glia, including strong inhibition of dendrite formation in Purkinje cells in the cerebellar cortex. Here we show that T3 promotes dendritic outg...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Hatsukano, Tetsu, Kurisu, Junko, Fukumitsu, Kansai, Fujishima, Kazuto, Kengaku, Mineko
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422430/
https://ncbi.nlm.nih.gov/pubmed/28536504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00133
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