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A Pragmatic Test for Detecting Association between a Dichotomous Trait and the Genotypes of Affected Families, Controls and Independent Cases

The efficient analysis of hybrid designs [e.g., affected families, controls, and (optionally) independent cases] is attractive because it should have increased power to detect associations between genetic variants and disease. However, the computational complexity of such an analysis is not trivial,...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wang, Meng, Stewart, William C. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422425/
https://ncbi.nlm.nih.gov/pubmed/28536599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00049
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