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Gene-Environment Interaction Tests for Dichotomous Traits in Trios and Sibships

When testing for genetic effects, failure to account for a gene-environment interaction can mask the true association effects of a genetic marker with disease. Family-based association tests are popular because they are completely robust to population substructure and model misspecification. However...

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Detalhes bibliográficos
Main Authors: Hoffmann, Thomas J., Lange, Christoph, Vansteelandt, Stijn, Laird, Nan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082448/
https://ncbi.nlm.nih.gov/pubmed/19365860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20421
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