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Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs

Histone deacetylases (HDACs) are key regulators of gene expression in cells and have been investigated as important therapeutic targets for cancer and other diseases. Different subtypes of HDACs appear to play disparate roles in the cells and are associated with specific diseases. Therefore, substan...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Yuren, Wallach, Jason, Duane, Stephanie, Wang, Yuan, Wu, Jianghong, Wang, Jeffrey, Adejare, Adeboye, Ma, Haiching
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5422321/
https://ncbi.nlm.nih.gov/pubmed/28496307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S124977
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