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Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs
Histone deacetylases (HDACs) are key regulators of gene expression in cells and have been investigated as important therapeutic targets for cancer and other diseases. Different subtypes of HDACs appear to play disparate roles in the cells and are associated with specific diseases. Therefore, substan...
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Publicado no: | Drug Des Devel Ther |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Dove Medical Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5422321/ https://ncbi.nlm.nih.gov/pubmed/28496307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S124977 |
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