Interleukin-22 promotes aerobic glycolysis associated with tumor progression via targeting hexokinase-2 in human colon cancer cells

Interleukin-22 has been explored extensively in human cancer, but its functions and underlying mechanisms are incompletely understood. Here, we show that aberrant interleukin-22 expression facilitates aerobic glycolysis in colon cancer cells. Elevated interleukin-22 mRNA expression was observed and...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: Liu, Yulin, Xiang, Fan, Huang, Yongming, Shi, Liang, Hu, Chaojie, Yang, Yiming, Wang, Di, He, Nan, Tao, Kaixiong, Wu, Ke, Wang, Guobin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2017
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421937/
https://ncbi.nlm.nih.gov/pubmed/28445985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15913
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