Suppression of allograft rejection by CD8+CD122+PD-1+ Tregs is dictated by their Fas ligand-initiated killing of effector T cells versus Fas-mediated own apoptosis

Mounting evidence has shown that naturally occurring CD8+CD122+ T cells are regulatory T cells (Tregs) that suppress both autoimmunity and alloimmunity. We have previously shown that CD8+CD122+PD-1+ Tregs not only suppress allograft rejection, but also are more potent in suppression than conventiona...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Huazhen, Wang, Yeshu, Zeng, Qiaohuang, Zeng, Yu-Qun, Liang, Chun-Ling, Qiu, Feifei, Nie, Hong, Dai, Zhenhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421838/
https://ncbi.nlm.nih.gov/pubmed/28445940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15551
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