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HbE/β-Thalassemia and Oxidative Stress: The Key to Pathophysiological Mechanisms and Novel Therapeutics

Significance: Oxidative stress and generation of free radicals are fundamental in initiating pathophysiological mechanisms leading to an inflammatory cascade resulting in high rates of morbidity and death from many inherited point mutation-derived hemoglobinopathies. Hemoglobin (Hb)E is the most com...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Hirsch, Rhoda Elison, Sibmooh, Nathawut, Fucharoen, Suthat, Friedman, Joel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421591/
https://ncbi.nlm.nih.gov/pubmed/27650096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6806
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