Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum

Mycobacterium africanum lineage (L) 6 is an important pathogen in West Africa, causing up to 40% of pulmonary tuberculosis (TB). The biology underlying the clinical differences between M. africanum and M. tuberculosis sensu stricto remains poorly understood. We performed ex vivo expression of 2179 g...

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Udgivet i:Tuberculosis (Edinb)
Main Authors: Ofori-Anyinam, Boatema, Dolganov, Gregory, Van, Tran, Davis, J. Lucian, Walter, Nicholas D., Garcia, Benjamin J., Voskuil, Marty, Fissette, Kristina, Diels, Maren, Driesen, Michèle, Meehan, Conor J., Yeboah-Manu, Dorothy, Coscolla, Mireia, Gagneux, Sebastien, Antonio, Martin, Schoolnik, Gary, Gehre, Florian, de Jong, Bouke C.
Format: Artigo
Sprog:Inglês
Udgivet: Churchill Livingstone 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421582/
https://ncbi.nlm.nih.gov/pubmed/28454650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2017.03.001
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