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Hyaluronan synthase assembles hyaluronan on a [GlcNAc(β1,4)](n)-GlcNAc(α1→)UDP primer and hyaluronan retains this residual chitin oligomer as a cap at the nonreducing end
Class I hyaluronan synthases (HAS) assemble [GlcNAc(β1,4)GlcUA(β1,3)](n)-UDP at the reducing end and also make chitin. Streptococcus equisimilis HAS (SeHAS) also synthesizes chitin-UDP oligosaccharides, (GlcNAc-β1,4)(n)-GlcNAc(α1→)UDP (Weigel et al. 2015). Here we determined if HAS uses chitin-UDPs...
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| Publicado no: | Glycobiology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421502/ https://ncbi.nlm.nih.gov/pubmed/28138013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwx012 |
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