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Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells
Endothelin (ET)-1 is an important peptide in cancer progression stimulating cellular proliferation, tumor angiogenesis and metastasis. ET-1 binds with high affinity to the ETA receptor (R) and ET(B)R on cancer cells. High levels of tumor ET-1 and ET(A)R are associated with poor survival of lung canc...
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Publicado no: | Peptides |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421360/ https://ncbi.nlm.nih.gov/pubmed/28153500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2017.01.012 |
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