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Spantide II, an effective tachykinin antagonist having high potency and negligible neurotoxicity.

Spantide (D-Arg1-Pro2-Lys3-Pro4-Gln5-Gln6-D-Trp7-Phe8-D-Trp9-++ +Leu10-Leu11-NH2) was introduced as a tachykinin antagonist in 1984 and has served as a starting point in the design of new antagonists that have proven to be more effective and have exhibited no neurological side effects. The most rema...

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Detalhes bibliográficos
Main Authors: Folkers, K, Feng, D M, Asano, N, Håkanson, R, Weisenfeld-Hallin, Z, Leander, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54212/
https://ncbi.nlm.nih.gov/pubmed/1693780
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