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Investigation of the specificity of FK 888 as a tachykinin NK1 receptor antagonist.

1. A recently described peptide tachykinin (NK1) receptor antagonist, FK 888, was found to inhibit the electrically-evoked, tachykinin-mediated contractile responses of the rabbit iris sphincter in a concentration-dependent manner; the pIC50 value was 6.6 +/- 0.08. 2. Contractions induced by a selec...

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Bibliografski detalji
Glavni autori: Wang, Z. Y., Tung, S. R., Strichartz, G. R., Håkanson, R.
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1910150/
https://ncbi.nlm.nih.gov/pubmed/7518299
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