All-D amino acid-containing channel-forming antibiotic peptides.

The D enantiomers of three naturally occurring antibiotics--cecropin A, magainin 2 amide, and melittin--were synthesized. In addition, the D enantiomers of two synthetic chimeric cecropin-melittin hybrid peptides were prepared. Each D isomer was shown by circular dichroism to be a mirror image of th...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Wade, D, Boman, A, Wåhlin, B, Drain, C M, Andreu, D, Boman, H G, Merrifield, R B
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1693777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4761
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