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Welcoming β-Catenin to the Gonadotropin-Releasing Hormone Transcriptional Network in Gonadotropes

GnRH binds its G-coupled protein receptor, GnRHR, on pituitary gonadotropes and stimulates transcription of Cga, Lhb, and Fshb. These three genes encode two heterodimeric glycoprotein hormones, LH and FSH, that act as gonadotropins by regulating gametogenesis and steroidogenesis in both the testes a...

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Publicado en:Mol Endocrinol
Autores principales: Salisbury, Travis B., Binder, April K., Nilson, John H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419541/
https://ncbi.nlm.nih.gov/pubmed/18218726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2007-0515
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