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GeneImp: Fast Imputation to Large Reference Panels Using Genotype Likelihoods from Ultralow Coverage Sequencing

We address the task of genotype imputation to a dense reference panel given genotype likelihoods computed from ultralow coverage sequencing as inputs. In this setting, the data have a high-level of missingness or uncertainty, and are thus more amenable to a probabilistic representation. Most existin...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Spiliopoulou, Athina, Colombo, Marco, Orchard, Peter, Agakov, Felix, McKeigue, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419496/
https://ncbi.nlm.nih.gov/pubmed/28348060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.200063
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