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Epidermal Growth Factor-Induced GnRH-II Synthesis Contributes to Ovarian Cancer Cell Invasion

GnRH-II modulates ovarian cancer cells invasion and is expressed in normal ovary and ovarian epithelial cancer cells; however, the upstream regulator(s) of GnRH-II expression in these cells remains unclear. We now demonstrate that epidermal growth factor (EGF) increases GnRH-II mRNA levels in severa...

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Détails bibliographiques
Publié dans:Mol Endocrinol
Auteurs principaux: Poon, Song Ling, Hammond, Gareth T., Leung, Peter C. K.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419146/
https://ncbi.nlm.nih.gov/pubmed/19608641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0147
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