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37-kDa Laminin Receptor Precursor Mediates GnRH-II–Induced MMP-2 Expression and Invasiveness in Ovarian Cancer Cells
GnRH-II enhances ovarian cancer cell invasion in an autocrine manner. We have now found that GnRH-II increases 37-kDa laminin receptor precursor (LRP) production in GnRH receptor (GnRHR)-positive OVCAR-3 and CaOV-3 ovarian cancer cells, while small interfering RNA (siRNA)-mediated depletion of GnRH-...
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| Publicado no: | Mol Endocrinol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417312/ https://ncbi.nlm.nih.gov/pubmed/21193558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0334 |
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