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GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression

STUDY HYPOTHESIS: We hypothesized that Runt-related transcription factor 2 (RUNX2), matrix metalloproteinase (MMP)2 and MMP9 are involved in basal and gonadotrophin-releasing hormone (GnRH)-induced human extravillous trophoblast (EVT) cell invasion. STUDY FINDING: Our finding indicates that GnRH-ind...

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Detalhes bibliográficos
Publicado no:Mol Hum Reprod
Main Authors: Peng, Bo, Zhu, Hua, Klausen, Christian, Ma, Liyang, Wang, Yan-ling, Leung, Peter C.K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733226/
https://ncbi.nlm.nih.gov/pubmed/26660506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molehr/gav070
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