Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approaches

For therapeutic monoclonal antibodies (mAbs), detailed analysis of the structural integrity and heterogeneity, which results from multiple types of post-translational modifications (PTMs), is relevant to various processes, including product characterization, storage stability and quality control. De...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Yang, Yang, Wang, Guanbo, Song, Ting, Lebrilla, Carlito B., Heck, Albert J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5419080/
https://ncbi.nlm.nih.gov/pubmed/28281873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1290033
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