Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

BACKGROUND: The burden of subclinical atherosclerosis in asymptomatic individuals is heritable and associated with elevated risk of developing clinical coronary heart disease (CHD). We sought to identify genetic variants in protein-coding regions associated with subclinical atherosclerosis and the r...

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Pubblicato in:Circ Cardiovasc Genet
Autori principali: Natarajan, Pradeep, Bis, Joshua C., Bielak, Lawrence F., Cox, Amanda J., Dörr, Marcus, Feitosa, Mary F., Franceschini, Nora, Guo, Xiuqing, Hwang, Shih-Jen, Isaacs, Aaron, Jhun, Min A, Kavousi, Maryam, Li-Gao, Ruifang, Lyytikäinen, Leo-Pekka, Marioni, Riccardo E., Schminke, Ulf, Stitziel, Nathan O., Tada, Hayato, van Setten, Jessica, Smith, Albert V., Vojinovic, Dina, Yanek, Lisa R., Yao, Jie, Yerges-Armstrong, Laura M., Amin, Najaf, Baber, Usman, Borecki, Ingrid B., Jeffrey Carr, J., Chen, Yii-Der Ida, Adrienne Cupples, L., de Jong, Pim A., de Koning, Harry, de Vos, Bob D., Demirkan, Ayse, Fuster, Valentin, Franco, Oscar H., Goodarzi, Mark O., Harris, Tamara B., Heckbert, Susan R., Heiss, Gerardo, Hoffmann, Udo, Hofman, Albert, Išgum, Ivana, Wouter Jukema, J., Kähönen, Mika, Kardia, Sharon L.R., Kral, Brian G., Launer, Lenore J., Massaro, Joe, Mehran, Roxana, Mitchell, Braxton D., Mosley, Thomas H., de Mutsert, Renée, Newman, Anne B., Nguyen, Khanh-dung, North, Kari E., O'Connell, Jeffrey R., Oudkerk, Matthijs, Pankow, James S., Peloso, Gina M., Post, Wendy, Province, Michael A., Raffield, Laura M., Raitakari, Olli T., Reilly, Dermot F., Rivadeneira, Fernando, Rosendaal, Frits, Sartori, Samantha, Taylor, Kent D., Teumer, Alexander, Trompet, Stella, Turner, Stephen T., Uitterlinden, Andre G., Vaidya, Dhananjay, van der Lugt, Aad, Völker, Uwe, Wardlaw, Joanna M., Wassel, Christina L., Weiss, Stefan, Wojczynski, Mary K., Becker, Diane M., Becker, Lewis C., Boerwinkle, Eric, Bowden, Donald W., Deary, Ian J., Dehghan, Abbas, Felix, Stephan B., Gudnason, Vilmundur, Lehtimäki, Terho, Mathias, Rasika, Mook-Kanamori, Dennis O., Psaty, Bruce M., Rader, Daniel J., Rotter, Jerome I., Wilson, James G., van Duijn, Cornelia M., Völzke, Henry, Kathiresan, Sekar, Peyser, Patricia A., O'Donnell, Christopher J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418659/
https://ncbi.nlm.nih.gov/pubmed/27872105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.116.001572
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