The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.
The CpG dinucleotide is present at approximately 20% of its expected frequency in vertebrate genomes, a deficiency thought due to a high mutation rate from the methylated form of CpG to TpG and CpA. We examine the hypothesis that the 20% frequency represents an equilibrium between rate of creation o...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2352943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.12.4692 |
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