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The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.

The CpG dinucleotide is present at approximately 20% of its expected frequency in vertebrate genomes, a deficiency thought due to a high mutation rate from the methylated form of CpG to TpG and CpA. We examine the hypothesis that the 20% frequency represents an equilibrium between rate of creation o...

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Detalhes bibliográficos
Main Authors: Sved, J, Bird, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC54183/
https://ncbi.nlm.nih.gov/pubmed/2352943
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