Expansion of myeloid‐derived suppressor cells with aging in the bone marrow of mice through a NF‐κB‐dependent mechanism

With aging, there is progressive loss of tissue homeostasis and functional reserve, leading to an impaired response to stress and an increased risk of morbidity and mortality. A key mediator of the cellular response to damage and stress is the transcription factor NF‐κB. We demonstrated previously t...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Flores, Rafael R., Clauson, Cheryl L., Cho, Joonseok, Lee, Byeong‐Chel, McGowan, Sara J., Baker, Darren J., Niedernhofer, Laura J., Robbins, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418207/
https://ncbi.nlm.nih.gov/pubmed/28229533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12571
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