Age‐related decline in BubR1 impairs adult hippocampal neurogenesis

Aging causes significant declines in adult hippocampal neurogenesis and leads to cognitive disability. Emerging evidence demonstrates that decline in the mitotic checkpoint kinase BubR1 level occurs with natural aging and induces progeroid features in both mice and children with mosaic variegated an...

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Gepubliceerd in:Aging Cell
Hoofdauteurs: Yang, Zhongxi, Jun, Heechul, Choi, Chan‐II, Yoo, Ki Hyun, Cho, Chang Hoon, Hussaini, Syed Mohammed Qasim, Simmons, Ambrosia J., Kim, Seonhee, van Deursen, Jan M., Baker, Darren J., Jang, Mi‐Hyeon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418205/
https://ncbi.nlm.nih.gov/pubmed/28383136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12594
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