The progeroid gene BubR1 regulates axon myelination and motor function

Myelination, the process by which oligodendrocytes form the myelin sheath around axons, is key to axonal signal transduction and related motor function in the central nervous system (CNS). Aging is characterized by degenerative changes in the myelin sheath, although the molecular underpinnings of no...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Choi, Chan-Il, Yoo, Ki Hyun, Qasim Hussaini, Syed Mohammed, Tak Jeon, Byeong, Welby, John, Gan, Haiyun, Scarisbrick, Isobel A., Zhang, Zhiguo, Baker, Darren J., van Deursen, Jan M., Rodriguez, Moses, Jang, Mi-Hyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191862/
https://ncbi.nlm.nih.gov/pubmed/27922816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101032
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