The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice

Calorie restriction (CR) remains the most robust intervention to extend lifespan and improve health span. Using a global mass spectrometry‐based metabolomic approach, we identified 193 metabolites that were significantly differentially expressed (SDE) in the livers of C57BL/6 mice, fed graded levels...

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Publicado en:Aging Cell
Autores principales: Green, Cara L., Mitchell, Sharon E., Derous, Davina, Wang, Yingchun, Chen, Luonan, Han, Jing‐Dong J., Promislow, Daniel E. L., Lusseau, David, Douglas, Alex, Speakman, John R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418186/
https://ncbi.nlm.nih.gov/pubmed/28139067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12570
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