A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase

Hyaluronan (HA) is an extremely large polysaccharide (glycosaminoglycan) involved in many cellular functions. HA catabolism is thought to involve the initial cleavage of extracellular high-molecular-weight (HMW) HA into intermediate-size HA by an extracellular or cell-surface hyaluronidase, internal...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Yamamoto, Hayato, Tobisawa, Yuki, Inubushi, Toshihiro, Irie, Fumitoshi, Ohyama, Chikara, Yamaguchi, Yu
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5418033/
https://ncbi.nlm.nih.gov/pubmed/28246172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770149
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