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Palovarotene inhibits osteochondroma formation in a mouse model of multiple hereditary exostoses(†)

Multiple hereditary exostoses (MHE), also known as multiple osteochondromas (MO), is an autosomal dominant disorder characterized by the development of multiple cartilage-capped bone tumors (osteochondromas). The large majority of patients with MHE carry loss-of-function mutations in the EXT1 or EXT...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Inubushi, Toshihiro, Lemire, Isabelle, Irie, Fumitoshi, Yamaguchi, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895492/
https://ncbi.nlm.nih.gov/pubmed/29120519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3341
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