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Hydrogen Peroxide Mediates EGF-Induced Down-Regulation of E-Cadherin Expression via p38 MAPK and Snail in Human Ovarian Cancer Cells

In ovarian cancer, it has been shown that E-cadherin is down-regulated by epidermal growth factor (EGF) receptor (EGFR) activation, and that cells with low E-cadherin expression are particularly invasive. Although it is generally believed that reactive oxygen species play important roles in intracel...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Principais autores: Cheng, Jung-Chien, Klausen, Christian, Leung, Peter C. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417450/
https://ncbi.nlm.nih.gov/pubmed/20610539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0034
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