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Transforming Growth Factor-β1 Inhibits Trophoblast Cell Invasion by Inducing Snail-mediated Down-regulation of Vascular Endothelial-cadherin Protein

Human trophoblast cells express transforming growth factor-β (TGF-β) and TGF-β receptors. It has been shown that TGF-β1 treatment decreases the invasiveness of trophoblast cells. However, the molecular mechanisms underlying TGF-β1-decreased trophoblast invasion are still not fully understood. In the...

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Autori principali: Cheng, Jung-Chien, Chang, Hsun-Ming, Leung, Peter C. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829165/
https://ncbi.nlm.nih.gov/pubmed/24106276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.488866
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