Induction of 11β-HSD 1 and Activation of Distinct Mineralocorticoid Receptor- and Glucocorticoid Receptor-Dependent Gene Networks in Decidualizing Human Endometrial Stromal Cells

The actions of glucocorticoids at the feto-maternal interface are not well understood. Here, we show that decidualization of human endometrial stromal cells (HESCs) in response to progesterone and cAMP signaling is associated with a strong induction of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD...

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Bibliographic Details
Published in:Mol Endocrinol
Main Authors: Kuroda, Keiji, Venkatakrishnan, Radha, Salker, Madhuri S., Lucas, Emma S., Shaheen, Fozia, Kuroda, Masako, Blanks, Andrew, Christian, Mark, Quenby, Siobhan, Brosens, Jan J.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417328/
https://ncbi.nlm.nih.gov/pubmed/23275455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1247
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