Elevated Periimplantation Uterine Natural Killer Cell Density in Human Endometrium Is Associated With Impaired Corticosteroid Signaling in Decidualizing Stromal Cells

BACKGROUND: Decidualizing human endometrial stromal cells (HESCs) profoundly up-regulate 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1), the enzyme that converts inert cortisone to active cortisol. We postulated that the induction of a cortisol gradient upon decidualization of the periimplantatio...

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Главные авторы: Kuroda, Keiji, Venkatakrishnan, Radha, James, Sean, Šućurović, Sandra, Mulac-Jericevic, Biserka, Lucas, Emma S., Takeda, Satoru, Shmygol, Anatoly, Brosens, Jan J., Quenby, Siobhan
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2013
Предметы:
Endocrine Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207949/
https://ncbi.nlm.nih.gov/pubmed/24025400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-1977
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