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Crystal structure of CD27 in complex with a neutralizing noncompeting antibody
CD27 is a T-cell and B-cell co-stimulatory glycoprotein of the tumor necrosis factor (TNF) receptor superfamily that is dependent on the availability of the TNF-like ligand CD70. Therapeutic approaches to treating autoimmune diseases and cancers with antagonistic and agonistic anti-CD27 monoclonal a...
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| 發表在: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
International Union of Crystallography
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417320/ https://ncbi.nlm.nih.gov/pubmed/28471362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X17005957 |
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