Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity of the Androgen Receptor and Significance for Prostate Cancer

Prostate tumor growth initially depends on androgens, which act via the androgen receptor (AR). Despite androgen ablation therapy, tumors eventually progress to a castrate-resistant stage in which the AR remains active. The mechanisms are poorly understood but it may be that changes in levels or act...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Reebye, Vikash, Querol Cano, Laia, Lavery, Derek N., Brooke, Greg N., Powell, Sue M., Chotai, Deepa, Walker, Marjorie M., Whitaker, Hayley C., Wait, Robin, Hurst, Helen C., Bevan, Charlotte L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416955/
https://ncbi.nlm.nih.gov/pubmed/22899854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1056
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