Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity of the Androgen Receptor and Significance for Prostate Cancer

Prostate tumor growth initially depends on androgens, which act via the androgen receptor (AR). Despite androgen ablation therapy, tumors eventually progress to a castrate-resistant stage in which the AR remains active. The mechanisms are poorly understood but it may be that changes in levels or act...

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Podrobná bibliografie
Vydáno v:Mol Endocrinol
Hlavní autoři: Reebye, Vikash, Querol Cano, Laia, Lavery, Derek N., Brooke, Greg N., Powell, Sue M., Chotai, Deepa, Walker, Marjorie M., Whitaker, Hayley C., Wait, Robin, Hurst, Helen C., Bevan, Charlotte L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416955/
https://ncbi.nlm.nih.gov/pubmed/22899854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1056
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