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The Hsp90 Cochaperone p23 Is Essential for Perinatal Survival

The functions of molecular chaperones have been extensively investigated biochemically in vitro and genetically in bacteria and yeast. We have embarked on a functional genomic analysis of the Hsp90 chaperone machine in the mouse by disrupting the p23 gene using a gene trap approach. p23 is an Hsp90...

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Autori principali: Grad, Iwona, McKee, Thomas A., Ludwig, Sara M., Hoyle, Gary W., Ruiz, Patricia, Wurst, Wolfgang, Floss, Thomas, Miller, Charles A., Picard, Didier
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636834/
https://ncbi.nlm.nih.gov/pubmed/17000766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-06
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