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The Hsp90 Cochaperone p23 Is Essential for Perinatal Survival

The functions of molecular chaperones have been extensively investigated biochemically in vitro and genetically in bacteria and yeast. We have embarked on a functional genomic analysis of the Hsp90 chaperone machine in the mouse by disrupting the p23 gene using a gene trap approach. p23 is an Hsp90...

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Detalhes bibliográficos
Main Authors: Grad, Iwona, McKee, Thomas A., Ludwig, Sara M., Hoyle, Gary W., Ruiz, Patricia, Wurst, Wolfgang, Floss, Thomas, Miller, Charles A., Picard, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636834/
https://ncbi.nlm.nih.gov/pubmed/17000766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-06
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