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The Hsp90 Cochaperone p23 Is Essential for Perinatal Survival

The functions of molecular chaperones have been extensively investigated biochemically in vitro and genetically in bacteria and yeast. We have embarked on a functional genomic analysis of the Hsp90 chaperone machine in the mouse by disrupting the p23 gene using a gene trap approach. p23 is an Hsp90...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grad, Iwona, McKee, Thomas A., Ludwig, Sara M., Hoyle, Gary W., Ruiz, Patricia, Wurst, Wolfgang, Floss, Thomas, Miller, Charles A., Picard, Didier
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636834/
https://ncbi.nlm.nih.gov/pubmed/17000766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-06
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