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Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model
The Hsp90 family of molecular chaperones includes the cytosolic isoforms Hsp90a and Hsp90β and the mitochondrial isoform Trap1. Hsp90a/βsupport a large number of client proteins in the cytoplasm and the nucleus whereas Trap1 regulates oxidative phosphorylation in mitochondria. Many of the associated...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392260/ https://ncbi.nlm.nih.gov/pubmed/28407697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15659 |
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