Sustained Inhibition of HBV Replication In Vivo after Systemic Injection of AAVs Encoding Artificial Antiviral Primary MicroRNAs

Chronic infection with hepatitis B virus (HBV) remains a problem of global significance and improving available treatment is important to prevent life-threatening complications arising in persistently infected individuals. HBV is susceptible to silencing by exogenous artificial intermediates of the...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Maepa, Mohube Betty, Ely, Abdullah, Grayson, Wayne, Arbuthnot, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415967/
https://ncbi.nlm.nih.gov/pubmed/28624194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.04.007
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