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Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells

One of the promising strategies to overcome tumor multidrug resistance (MDR) is to deliver anticancer drug along with P-glycoprotein (P-gp) inhibitor simultaneously. To enhance the cancer cellular internalization and implement the controlled drug release, herein an iRGD peptide-modified lipid-polyme...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zhang, Jinming, Wang, Lu, Fai Chan, Hon, Xie, Wei, Chen, Sheng, He, Chengwei, Wang, Yitao, Chen, Meiwan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415764/
https://ncbi.nlm.nih.gov/pubmed/28470171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46057
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