Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex

In chronic lymphocytic leukemia (CLL), STAT3 is constitutively phosphorylated on serine 727 and plays a role in the pathobiology of CLL. However, what induces constitutive phosphorylation of STAT3 is currently unknown. Mass spectrometry was used to identify casein kinase 2 (CK2), a serine/threonine...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Jain, Preetesh, Veletic, Ivo, Ferrajoli, Alessandra, Burger, Jan, O’Brien, Susan, Bose, Prithviraj, Thompson, Philip, Jain, Nitin, Wierda, William, Keating, Michael J., Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415425/
https://ncbi.nlm.nih.gov/pubmed/28130399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0291
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