Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis

Oncolytic vaccinia virus (VACV) therapy is an alternative cancer treatment modality that mediates targeted tumor destruction through a tumor-selective replication and an induction of anti-tumor immunity. We developed a humanized tumor mouse model with subcutaneous human tumors to analyze the interac...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Tsoneva, Desislava, Minev, Boris, Frentzen, Alexa, Zhang, Qian, Wege, Anja K., Szalay, Aladar A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415323/
https://ncbi.nlm.nih.gov/pubmed/28480327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2017.03.001
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