A One-Step PCR-Based Assay to Evaluate the Efficiency and Precision of Genomic DNA-Editing Tools

Despite rapid progress, many problems and limitations persist and limit the applicability of gene-editing techniques. Making use of meganucleases, TALENs, or CRISPR/Cas9-based tools requires an initial step of pre-screening to determine the efficiency and specificity of the designed tools. This step...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Mol Ther Methods Clin Dev
Главные авторы: Germini, Diego, Bou Saada, Yara, Tsfasman, Tatiana, Osina, Kristina, Robin, Chloé, Lomov, Nikolay, Rubtsov, Mikhail, Sjakste, Nikolajs, Lipinski, Mar≿, Vassetzky, Yegor
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2017
Предметы:
Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415314/
https://ncbi.nlm.nih.gov/pubmed/28480303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.03.001
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы